University College London
The Neuromuscular Centre at the Institute of Child Health has a longstanding tradition of excellence in the field of diagnosis, management and care of childhood neuromuscular conditions. The strength of the unit is the large critical mass of patients, the diagnostic pathology expertise together with an active program of research and key national and international collaborations.
The Neuromuscular Centre follows the largest cohort of children affected by neuromuscular conditions in UK and have an active role in networking the remaining UK Units; Francesco Muntoni is the PI in a phase I/II trial using antisense oligonucleotides in DMD in UK. The Centre has an active program of research on muscular dystrophy, which led to the identification of 5 novel genes in the last few years.
The Cochrane Neuromuscular Disease Group has been based in the MRC Centre for Neuromuscular Diseases at the Institute of Neurology, University College London since September 2008. The group aims to provide systematic reviews of all interventions for all neuromuscular diseases, including amyotrophic lateral sclerosis/motor neuron disease, peripheral nerve disorders, myasthenia gravis and neuromuscular function disorders, and of particular interest to the TREAT NMD Network, systematic reviews of interventions for muscle diseases. From our total of 82 published reviews, the group has now published 23 systematic reviews of direct relevance to TREAT NMD and has a further 11 reviews in preparation. The group’s joint co-ordinating editors are now Dr Michael Lunn and Dr Rosaline Quinlivan. Professor Richard Hughes remains on the editorial board.