Professor of Pharmacology
Paola Imbrici is a pharmacologist with a long standing interest in the study of genetic channelopathies of skeletal muscle, brain and kidney and their pharmacotherapy. The main aims of her research are: i) investigating the molecular mechanisms underlying channelopathies and defining the genotype-phenotype correlation in affected patients; ii) developing personalized therapies for channelopathies based on pharmacogenetics, newly synthesized molecules and/or drug repositioning. This research is based on functional and pharmacological in vitro and in vivo studies using cell-lines and animal models and patients’ biopsies and on different approaches ranging from patch-clamp electrophysiology to biochemical, molecular biology to more functional assays to assess drug efficacy. Paola Imbrici’s research is performed in close collaborations with several clinical centres and other academic laboratories.
Department of Pharmacy - Drug Sciences, University of Bari "Aldo Moro"