Postdoctoral Research in Myositis

Johns Hopkins University School of Medicine

Closing date: 30 August 2019
Contact: tlloyd4@jhmi.edu

A postdoctoral position is available at Johns Hopkins University School of Medicine in Baltimore, Maryland, USA, to study a xenograft mouse model of myositis in the laboratory of Thomas E. Lloyd, MD, PhD. In this model, human muscle biopsies are transplanted into immunodeficient mice, and the human muscle biopsies are transplanted into immunodeficient mice, and the human muscle regenerates and is rennervated and revascularized by the mouse host.  This exciting precision medicine initiative will use state-of-the art technologies to explore the interaction between the immune system and regenerating between the immune system and regenerating muscle in autoimmune myopathies such as inclusion body myositis, immune-mediated necrotizing myopathy, and dermatomyositis. Expertise in immunology, myology, or mouse models of neuromuscular disease is preferred. The Lloyd laboratory uses a combination of genetic, molecular, cellular, physiologic, and imaging approaches in Drosophila, mouse, and iPS models in addition to human brain and muscle tissue to study the cell
biology of degenerative diseases affecting the neuromuscular system.

Recent relevant publications include: Zhang K et al (2018) Cell 173:958; Britson KA (2018) Curr Rheumatol Rep 20:26; Lloyd TE et al (2017) Neurology 88:1454; Zhang K et al (2015) Nature 525:56.

Highly motivated and energetic candidates with a strong publication record are encouraged to apply. Interested applicants should send curriculum vitae to tlloyd4@jhmi.edu.